Serveur d'exploration sur la maladie de Parkinson

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Differential Effects of Black versus Green Tea on Risk of Parkinson's Disease in the Singapore Chinese Health Study

Identifieur interne : 000C03 ( Main/Exploration ); précédent : 000C02; suivant : 000C04

Differential Effects of Black versus Green Tea on Risk of Parkinson's Disease in the Singapore Chinese Health Study

Auteurs : Louis C. Tan ; Woon-Puay Koh [Singapour] ; Jian-Min Yuan ; Renwei Wang ; Wing-Lok Au ; June H. Tan ; Eng-King Tan ; Mimi C. Yu

Source :

RBID : ISTEX:DE1DC0DA0F885D18D18E72BE2810C91D76AA834B

Abstract

Data from Asian populations on dietary and lifestyle factors associated with Parkinson's disease are sparse. In 19932005, the authors examined these factors in relation to Parkinson's disease in the Singapore Chinese Health Study, a prospective cohort of 63,257 Chinese men and women. Baseline data were collected through in-person interviews using structured questionnaires. All 157 incident Parkinson's disease cases were identified either through follow-up interviews or via linkage with hospital discharge databases and Parkinson's disease outpatient registries and were confirmed by review of medical records. Current versus never smokers exhibited a reduced risk of Parkinson's disease (relative risk 0.29, 95% confidence interval: 0.16, 0.52). Total caffeine intake was inversely related to Parkinson's disease risk (p for trend 0.002); the relative risk for the highest versus lowest quartile was 0.55 (95% confidence interval: 0.35, 0.88). Black tea, a caffeine-containing beverage, showed an inverse association with Parkinson's disease risk that was not confounded by total caffeine intake or tobacco smoking (p for trend 0.0006; adjusted relative risk for the highest vs. lowest tertile of intake 0.29, 95% confidence interval: 0.13, 0.67). Green tea drinking was unrelated to Parkinson's disease risk. Diet had no strong influence on risk. Ingredients of black tea other than caffeine appear to be responsible for the beverage's inverse association with Parkinson's disease.

Url:
DOI: 10.1093/aje/kwm338


Affiliations:


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<div type="abstract">Data from Asian populations on dietary and lifestyle factors associated with Parkinson's disease are sparse. In 19932005, the authors examined these factors in relation to Parkinson's disease in the Singapore Chinese Health Study, a prospective cohort of 63,257 Chinese men and women. Baseline data were collected through in-person interviews using structured questionnaires. All 157 incident Parkinson's disease cases were identified either through follow-up interviews or via linkage with hospital discharge databases and Parkinson's disease outpatient registries and were confirmed by review of medical records. Current versus never smokers exhibited a reduced risk of Parkinson's disease (relative risk 0.29, 95% confidence interval: 0.16, 0.52). Total caffeine intake was inversely related to Parkinson's disease risk (p for trend 0.002); the relative risk for the highest versus lowest quartile was 0.55 (95% confidence interval: 0.35, 0.88). Black tea, a caffeine-containing beverage, showed an inverse association with Parkinson's disease risk that was not confounded by total caffeine intake or tobacco smoking (p for trend 0.0006; adjusted relative risk for the highest vs. lowest tertile of intake 0.29, 95% confidence interval: 0.13, 0.67). Green tea drinking was unrelated to Parkinson's disease risk. Diet had no strong influence on risk. Ingredients of black tea other than caffeine appear to be responsible for the beverage's inverse association with Parkinson's disease.</div>
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   |texte=   Differential Effects of Black versus Green Tea on Risk of Parkinson's Disease in the Singapore Chinese Health Study
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